Date & Time:
February 23, 2021 10:00-11:00am PST / 1:00 – 2:00pm EST
SPEAKER: YUETIAN YAN, PH.D.
STAFF SCIENTIST @ REGENERON PHARMACEUTICALS
In this webinar, Dr. Yan will describe the development of a versatile, sensitive, and robust native LC−MS platform that can support various native LC−MS applications. The platform can tolerate a wide range of LC flow rates and high salt concentrations, which are critical for accommodating different nLC methods. In addition, a dopant-modified desolvation gas can be readily applied on this platform to achieve online charge-reduction native MS, which improves the characterization of both heterogeneous and labile biomolecules. This platform can be routinely applied in protein drug characterization.